The Wakamoto lab is aimed at gaining deep understanding of general biological phenomena such as growth, adaptation, evolution, and differentiation, utilizing model cell systems (bacteria, yeast, and cancer cells).

Biology is diverse, but also full of common properties and rules across the species. We investigate the origin and the biological significance of those commonalities both theoretically and experimentally, hoping to provide some comprehensible foundations for modern biological studies.

Examples of research topics

• Phenotypic adaptation under stressful conditions
• Paving the way for live-cell omics by Raman microscopy
• Growth noise under constant environmental conditions and phenomenological rules
• Inferring fitness landscapes and selection on phenotypic states
• Development of single-cell measurement and analysis tools